Creutzfeldt-Jakob Disease

This biomarker information is intended to be used by scientists for research purposes.

Scientific Articles

1959

  • Observations on kuru. III: Pathological features in five cases

1963

  • Creutzfeldt-Jakob’s disease. Clinicopathologic report of 15 cases and review of the literature (with special reference to a related disorder designated as subacute spongiform encephalopathy).

1965

  • An ataxic form of subacute presenile polioencephalopathy (Creutzfeldt-Jakob disease)

1966

  • Experimental „kuru“ in chimpanzees. A pathological report

1968

  • Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee

1969

  • Creutzfeldt-Jakob disease. The neuropathology of a transmission experiment
  • Degenerative diseases of the central nervous system transmissible to experimental animals

1971

  • Kuru-plaques in a case of Creutzfeldt-Jakob disease

1973

  • Creutzfeldt-Jakob disease

1978

  • Incidence of Creutzfeldt-Jakob disease in Brooklyn and Staten Island

1979

  • Creutzfeldt-Jakob disease: patterns of worldwide occurrence and the significance of familial and sporadic clustering

1985

  • Creutzfeldt-Jakob Disease

1987

  • The epidemiology of Creutzfeldt-Jakob disease: conclusion of a 15-year investigation in France and review of the world literature

1991

  • Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

1992

  • “Friendly fire” in medicine: hormones, homografts, and Creutzfeldt-Jakob disease

1996

  • A new variant of Creutzfeldt-Jakob disease in the UK
  • Risk factors for Creutzfeldt-Jakob disease: a reanalysis of case-control studies

1997

  • Creutzfeldt-Jakob disease associated with cadaveric dura mater grafts — Japan, January 1979-May 1996.
  • Creutzfeldt-Jakob disease in the elderly
  • Magnetic resonance imaging in Creutzfeldt-Jakob disease: evidence of focal involvement of the cortex

1998

  • Creutzfeldt-Jakob disease and related transmissible spongiform encephalopathies

1999

  • Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects

2000

  • Magnetic resonance imaging in the clinical diagnosis of Creutzfeldt-Jakob disease.
  • Creutzfeldt-Jakob disease in the United States: 1979-1998

2001

  • MRI of Creutzfeldt-Jakob disease: imaging features and recommended MRI protocol.

2002

  • Creutzfeldt-Jakob disease cluster in an Australian rural city

2003

  • Update: Creutzfeldt-Jakob disease associated with cadaveric dura mater grafts–Japan, 1979-2003.

2004

  • Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies
  • Sporadic Creutzfeldt-Jakob disease: magnetic resonance imaging and clinical findings.

2005

  • Clinical course in young patients with sporadic Creutzfeldt-Jakob disease.
  • Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada.
  • MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease: a study on inter-observer agreement.

2006

  • Creutzfeldt-Jakob disease among American Indians and Alaska Natives in the United States.

2007

  • Clinical features and diagnosis of dura mater graft associated Creutzfeldt Jakob disease.

2008

  • Iatrogenic Creutzfeldt-Jakob disease 22 years after human growth hormone therapy: clinical and radiological features.
  • Risk factors for sporadic Creutzfeldt-Jakob disease.

2009

  • Characteristics of established and proposed sporadic Creutzfeldt-Jakob disease variants
  • Enhanced geographically restricted surveillance simulates sporadic Creutzfeldt-Jakob disease cluster.
  • Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease

2012

  • Sporadic human prion diseases: molecular insights and diagnosis

Biomarkers

14-3-3 Protein

  • 14-3-3 protein detection and sporadic CJD: the status quo serves well while awaiting progress
  • Detection of 14-3-3 protein in the CSF of genetic Creutzfeldt-Jakob disease
  • Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease
  • Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease
  • Establishment of a standard 14-3-3 protein assay of cerebrospinal fluid as a diagnostic tool for Creutzfeldt-Jakob disease
  • Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease
  • Tau and 14-3-3 of genetic and sporadic Creutzfeldt-Jakob disease patients in Israel.
  • The role of cerebrospinal fluid 14-3-3 and other proteins in the diagnosis of sporadic Creutzfeldt-Jakob disease in the UK: a 10-year review.
  • Use of 14-3-3 and other brain-specific proteins in CSF in the diagnosis of variant Creutzfeldt-Jakob disease

Interleukin-4

  • Interleukin 4 and interleukin 10 levels are elevated in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease

Interleukin-10

  • Interleukin 4 and interleukin 10 levels are elevated in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease

Plasminogen

  • Cortical neurons of Creutzfeldt-Jakob disease patients express the urokinase-type plasminogen activator receptor
  • Plasminogen activities and concentrations in patients with sporadic Creutzfeldt-Jakob disease